Depigma Glocalcare | Glocalcare Official Site
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Spot-Less From Within

Depigma GlocalCare is a dietary supplement, formulated to support the body's tolerance and promote a healthy skin appearance. Our carefully selected blend of ingredients aims to work synergistically to support the reduction of skin blemishes, discoloration, and dark spots, including those caused by melasma and sun exposure. It naturally withens your skin from the inside out bringing zero harm.*

    • Regulates skin pigmentation process in all types of hyperpigmentation.*
    • Helps maintain a healthy, illuminating, and uniform skin.*
    • Helps combat pigmentary disorders induced by traumas, procedures, and sun exposure.*
    • Supports the skin against sun damage and sunburn.*
    • Detoxifies your skin.*
    • Provides a radiant even skin tone.*
    • Promotes anti-aging effects.*
    • Support the skin from the oxidative damage produced by free radicals.*
    • Whitening illuminating effects.*


1 capsule per day or according to doctor’s prescription


30 Capsules


L-glutathione, Polypodium leucotomos extract, Grape seed extract (Proanthocyanidines), Marigold Extract (Lutein), Vitamin E, Vitamin C, Vitamin B3.


Regulates skin pigmentation process & Help to maintain healthy, illuminating and uniform skin.*

Help to defeats pigmentary disorders induced by traumas and procedures.*



Support skin from the sun damage and sunburn & oxidative damage produced by free radicals.*  

Detoxifies your skin & Provides a radiant even skin tone.*



Promotes anti-aging effects & whitening illumination effects.*


The advanced engineering formula delivers a pure dose of Setria® L Glutathione known as a master antioxidant and detoxifier*. Additionally, this product includes a specific combination of powerful antioxidant plant extracts, such as Polypodium Leucotomos, Grape Seed Extract, and Marigold Extract*. These supporting ingredients may work synergistically to promote skin luminosity*.

Setria® Glutathione reduces melanin production by suppressing the activity of tyrosinase and switching the eumelanin synthesis to pheomelanin synthesis. * Free radical damage affects how well we age. As the body's "master antioxidant," glutathione protects cells against free radical damage, thereby supporting the normal functioning of tissues and organs.

Glutathione as an antioxidant fights oxidative stress for overall good health. * Glutathione is recognized as a great protector. Without glutathione, each cell would become so ravaged by free radicals that it would disintegrate.*

What sets our SETRIA® Glutathione apart:
  • Liposomal Delivery for Maximum Absorption.*
  • Maximum Antioxidant, Detox, Healthy Aging, and Immune Support.*
  • Patented &. Clinically Studied.*
  • Rigorously Quality Checked &. Lab Tested.*
  • Free of Fillers, Non-GMO, &. Gluten-Free.*




An adjunct Photoprotective agent in melasma

Polypodium leukotomos

Polypodium leucotomos, a fern native to Central and South America, wields potent properties against depigmentation. Its phytochemicals form a shield against sun rays, gently reducing melanin. Like a graceful dance, it harmonizes with the skin, bestowing a rejuvenating touch. The fern's ethereal partnership with light and green creates a balanced canvas for skin beauty and vitality.*

Proanthocyanidines (Vitis vinifera L.)

Grape seed extract (GSE) boasts potent antioxidants that counter free radicals and UV damage, reducing hyperpigmentation. It enhances collagen production, improving skin elasticity and reducing dark spots. GSE inhibits tyrosinase, lessening excess melanin for a brighter, more even complexion, making it a key ingredient in depigmentation skincare.*

Lutein/ zexanthin (Tagetes spp)


  • Lutein and zeaxanthin, potent antioxidants, combat depigmentation by countering oxidative stress and inflammation in the skin. They promote even skin tone and enhance collagen production, potentially aiding in depigmentation. Incorporating them through diet or supplements can support a balanced complexion.*


  • Synergistic for filtering blue light and protecting the skin from environmental factors.*
  • Reduce inflammation caused by eczema and dermatitis.*
  • Supports wound healing.*


Niacinamide (Vitamin B3) maintains healthy skin and inhibits melanin transfer. Vitamin C supports collagen formation, suppresses melanin production, and provides UV protection. Meanwhile, Vitamin E acts as a moisturizer and defends against premature aging with its antioxidants. Together, these vitamins play a vital role in maintaining even and vibrant skin, combating depigmentation, and protecting against environmental damage.*

Science backed Pharma- Grade ingredients

Setria® Glutathione

  • Help with removing Dark spots and acne scars.*
  • Support hyperpigmentation treatment.*
  • Gives an anti-aging effect and has powerful antioxidants.*

Polypodium Leukotomos Extract

  • Adjunct Photoprotective agent in melasma.*
  • Antioxidant properties.*
  • Anti-inflammatory -effects.*
  • Anti-aging benefits.*

Proanthocyanidines (Vitis Vinifera L.)

  • Antioxidant and anti-aging properties.*
  • Moisturizing benefits.*
  • Anti-dark spot effects.*
  • Clinically proven to lighten UV-induced hyperpigmentation.*

Lutein/Zexanthin (Tangetes Erecta L.)

  • Filters UV, blue light & high-energy sources.
  • Blocks the formation of melanin pathways.
  • Decrease cytokines.
  • Increase antioxidant activity of the skin.


Vitamins B3 (niacinamide), C and E contribute to the maintenance of normal skin and protect cells from oxidative damage. Additionally, vitamin C contributes to normal collagen formation for the normal function of skin.

All incoming row materials are tested for identity, potency, quality and cleanliness.

Depigma Glocalcare developed by following good manufacturing practice ( GMP ) in a certified , FDA registered facility with the highest quality ingredients and carefully inspected and quality-controlled to ensure the highest quality and purity.

Our packaging must protect products from the many changes in the environment. BLISTERS have a meaningful impact on product quality, child safety, and patient outcomes through improved adherence.

With a GLOCAL vision to:

Source Globally & manufacture Locally
Proudly in the USA